Artificial intelligence enters the field of oncological pathology: current applications and future prospects.
Artificial intelligence (AI) is rapidly transforming pathology and oncology, offering new opportunities to improve cancer diagnosis, prognosis, and treatment. This article reviews current applications of AI in tumor detection, molecular biomarker identification, and prognostic evaluation, as well as barriers and future prospects for its clinical adoption. AI, especially through deep neural networks, improves the detection […]
Stereotactic body radiation therapy in the treatment of bone metastases from various tumors.
Abstract Bone metastasis is a common complication in breast and prostate cancers, characterized by severe pain and a high risk of fractures. Its treatment includes several strategies, notably stereotactic body radiation therapy (SBRT). The objective of this study is to evaluate the efficacy of SBRT in pain control, the incidence of treatment-related fractures, and to […]
Synchronous multiple primary lung neoplasia. Hamartoma as the primary tumor and lung adenocarcinoma.
Abstract The presence of multiple primary lung neoplasms is uncommon, with few series described in the literature. They can manifest synchronously or metachronously, with the latter being more common. The prognosis in patients with synchronous tumors appears to be more unfavorable than in patients with single lung neoplasms. METHOD. The research complied with ethical and […]
Open access in solitary nasosinusal neurofibroma.
Abstract BACKGROUND: Neurofibroma is a benign tumor originating from Schwann cells, characterized by its asymptomatic course, initially with slow progressive growth. It is a rare disease in the head and neck, reported in less than 4% of cases. CLINICAL CASE: A 23-year-old female patient whose condition began in 2019 with symptoms of right nasal obstruction, […]
Polymyositis secondary to paroxysmal nocturnal hemoglobinuria (PNH). Case report.
Abstract We present the case of a 35-year-old female patient with a previous diagnosis of paroxysmal nocturnal hemoglobinuria (PNH), treated with immunosuppressants and bone marrow stimulation therapy. She was admitted to the institution with severe pancytopenia, extreme fatigue, transvaginal bleeding, and desquamative skin lesions, progressing to septic shock, neurological compromise, and progressive proximal muscle weakness.Clinical, […]
Midline destructive syndrome in a case of extranodal T/NK lymphoma associated with Epstein-Barr virus infection in a young patient.
SUMMARY Introduction: Nasal extranodal T/NK (ENKEL-NT) lymphoma is a rare and aggressive form of non-Hodgkin lymphoma (NHL) associated with Epstein-Barr virus (EBV) infection. It is characterized by neoplastic proliferation of the T/NK cell lymphoreticular system. Its incidence varies, being common in regions such as Asia and Latin America. Clinical case: A 30-year-old male patient with […]
Hemoglobin, hematocrit, and diagnoses associated with red blood cell concentrate transfusion in a Neonatal Intensive Care Unit.
SUMMARY Introduction: Indiscriminate use of red blood cell concentrate transfusions can have adverse effects, so it is important to understand the trends in each hospital unit in order to implement and standardize criteria for transfusion indications and improve the quality of this therapeutic measure. Objective: To identify the hemoglobin and hematocrit values and diagnoses associated […]
Efficacy, safety, and satisfaction with the use of emicizumab in patients with hemophilia A without factor VIII inhibitors: a systematic review.
Abstract Introduction Hemophilia A is a genetic disorder characterized by deficiency or dysfunction of the coagulation protein factor VIII, leading to severe bleeding disorders. Conventional treatment consists of exogenous administration of factor VIII. However, this therapy presents significant challenges, such as the development of inhibitors and the need for frequent intravenous administration. Emicizumab, a recombinant […]
Hematological indices and cytokine profiles in heterozygous beta-thalassemia.
Abstract Introduction β-thalassemia is defined by a reduction or total absence of β-globin chain synthesis in hemoglobin, causing hemolytic anemia. Heterozygous β-thalassemia, also known as β-thalassemic trait (hBTh), the mildest form of this anemia, does not usually cause symptoms in carriers. However, it can cause alterations in the immune system, such as an increase in […]
Direct oral thrombin inhibitors or oral factor Xa inhibitors versus conventional anticoagulants for the treatment of pulmonary thromboembolism: a Cochrane review.
Simplified summary Title: Are direct oral anticoagulants (a type of “blood thinner”) better than traditional anticoagulants for treating pulmonary thromboembolism (blood clots in the lungs)? What is a pulmonary embolism? It is when a piece of a blood clot breaks off from another part of the body and travels through the blood to the lungs. […]