Fauci Successor Imminent; CDC Expands Outbreak List; Pesticides Linked to ALS
Note about Links Note that some links may require registration or subscription. Director of National Institute of Allergy and Infectious Diseases Biotech executive Steven Quay, MD, PhD, who supported the COVID lab leak theory, is in line to take over Anthony Fauci, MD’s old job as director of the National Institute of Allergy and Infectious […]
Evolving Landscape for Managing Cardiovascular, Renal and Metabolic Conditions
Introducción Boehringer Ingelheim’s Brian Hilberdink, President, U.S. Human Pharma, and Neerja Balachander, M.D., Ph.D., VP, U.S. Clinical Development Medical Affairs and Cardiorenal Metabolic Therapeutic Area Head, reflect on key developments and what lies ahead for cardiovascular, renal and metabolic care, including implications for obesity, liver disease and chronic kidney disease. Reflexiones sobre la situación actual […]
New ACG guideline outlines outpatient management of diverticulitis
Clinical takeaway: Most patients with acute uncomplicated diverticulitis do not require routine antibiotics. Management should emphasize CT-confirmed diagnosis, selective use of antibiotics and colonoscopy, counseling on evidence-based lifestyle measures to reduce recurrence, and individualized decisions about elective surgery. The American College of Gastroenterology (ACG) has released its first dedicated clinical guideline for outpatient management of […]
Daily tadalafil may increase glaucoma risk
Clinical takeaway: For men taking daily tadalafil for lower urinary tract symptoms due to benign prostatic hyperplasia, clinicians should consider glaucoma risk when discussing long-term therapy. Patients with pre-existing glaucoma, ocular hypertension, high myopia, or a family history of glaucoma may warrant baseline ophthalmic evaluation and periodic follow-up. Tadalafil is commonly prescribed as a daily […]
Biden’s Bedtime Cancer Symptom; Top Cancer Hospitals; FDA Panel to Review MCED Test
Síntomas de cáncer vistos por Jill Biden Former First Lady Jill Biden said she noticed a concerning symptom before former President Joe Biden was diagnosed with aggressive prostate cancer — he was waking up to use the bathroom up to seven times a night. (USA Today) Fallecimiento de influencer por cáncer raro Sydney Towle, an […]
Trump Considers Vaccine-Autism Order; McConnell Leaves Rehab; Lettuce Scare Eases
Vaccines and Autism Executive Order White House officials are considering an executive order addressing vaccines and autism, aligning with President Donald Trump’s push for increased federal action on the matter despite advisers’ warnings, according to a person familiar with the matter. (CNN) McConnell’s Recovery Sen. Mitch McConnell (R-Ky.) said he was discharged from a rehabilitation […]
COVID severity tied to reactivation of dormant viruses
Clinical takeaway: Reactivation of dormant herpesviruses tracked with COVID severity in immunocompetent patients, which widens the group of hospitalized patients in whom it may be worth considering. When a hospitalized COVID patient deteriorates in the second week, the differential is well-worn: bacterial superinfection, thromboembolism, progressive lung injury. Chronic viral reactivation rarely joins that list unless […]
Declaring Death Is Not So Simple
The first person I ever declared dead was a woman with cancer on hospital hospice care, when I was a medical student on my hematology-oncology rotation. The nurse told me the patient had passed, and it became my job to confirm it. The supervising resident stood with me and demonstrated the protocol: listen for breath […]
Mitch McConnell Breaks Silence, Says Hospitalization Was Due to a Fall
Sen. Mitch McConnell (R-Ky.) on Sunday revealed for the first time that a fall led to his hospitalization, breaking the silence about his condition after weeks of mounting speculationopens in a new tab or window about the 84-year-old’s health. McConnell said in a statement that he was “briefly unconscious” around the time he was first […]
PAM Inhibitor Approved for HR-Positive Breast Cancer
Introducción The FDA approved the kinase inhibitor gedatolisib (Revtorpyk) for treating hormone receptor (HR)-positive/HER2-negative breast cancer in patients whose disease has progressed on endocrine therapy in the metastatic setting. Detalles sobre la aprobación Approval of the PI3K/AKT/mTOR (PAM) inhibitor stipulates use in combination with fulvestrant — with or without the CDK4/6 inhibitor palbociclib (Ibrance) — […]