Introducción
After 11 infants were exposed to measles at a pediatric clinic in Utah, the state Department of Health and Human Services (DHHS) helped administer intramuscular immunoglobulin (IMIG) as postexposure prophylaxis (PEP) and ultimately developed a protocol for statewide use amid the ongoing outbreak.
None of the infants’ parents declined IMIG for their child, and there were no serious or localized systemic adverse events during administration or reported in follow-up calls, reported Anna Jones, MD, of DHHS and the CDC, and colleagues. Notably, none of the infants contracted measles during the 21-day monitoring period.
Protocolo y Resultados
IMIG administered at a dose of 0.5 ml/kg is an option for prophylaxis in infants following exposure to measles, the research team noted in a Public Health Alert in NEJM Evidence. However, weight-based dosing volumes require multiple or large-volume injections, and clear administration guidelines haven’t been available.
Fuente: https://www.medpagetoday.com/pediatrics/generalpediatrics/121378
Join the doctors who get the most relevant medical news, curated by specialty, every week — no spam, unsubscribe anytime.
