Early Sugar Exposure and Cancer Risk; Melanoma Vaccine Win; ‘Antifreeze’ for CAR-T

Reduced Sugar Exposure and Cancer Risk

People who had restricted sugar exposure during the first 2 years of life grew into adults with a lower risk of cancer. (American Journal of Clinical Nutrition)

Antioxidants and Cervical Cancer

Meanwhile, women who consumed a diet high in antioxidants had a lower risk of cervical cancer. (International Journal of Gynecology & Obstetrics)

FDA Decision on Leukemia Treatment

The FDA declined to approve Xspray Pharma’s investigational formulation of dasatinib for chronic myeloid leukemia and acute lymphoblastic leukemia due to manufacturing issues.

Retirement of a Major League Player

Major League Baseball player Trey Mancini, 34, announced his retirement from a career that included a Comeback Player of the Year award after taking a year off to get treatment for colon cancer. (ESPN)

Improving Melanoma Treatment

Adding the cancer vaccine intismeran autogene to pembrolizumab (Keytruda) significantly improved recurrence-free survival and distant metastasis-free survival in a phase III trial of completely resected melanoma. Merck and Moderna announced this progress.

New Treatment for Lung Cancer

The novel, first-in-class antibody-drug conjugate izalontamab brengitecan improved progression-free survival versus chemotherapy in progressive EGFR-mutated lung cancer. (Fierce Pharma)

Low Awareness of Lung Cancer Screening

Fewer than 15% of people eligible for lung cancer screening with low-dose CT have actually discussed screening with their doctors. (University of Cincinnati)

Longevity and Immune Cells

People who live to 100 or older have an abundance of cancer-fighting immune cells. (Cell Reports)

Using Sugars for Cell Preservation

A cell-preservation technique that uses naturally occurring sugars as “antifreeze” could help make CAR T-cell therapy more widely available. (MIT News)

Obesity Treatment for Cancer Survivors

Personalized obesity treatment that includes weight-loss medications may improve the long-term health of breast cancer survivors. (John Hopkins Medicine)

Obesity’s Impact on Lung Cancer

A study of lung cancer patients showed that obesity weakened the body’s cancer-fighting immune activity, but physical activity might help reverse that effect. (Roswell Park Comprehensive Cancer Center)

Increased Risks for Hodgkin Lymphoma Survivors

Five-year survivors of Hodgkin lymphoma still have an increased risk of earlier death from non-cancer conditions, particularly cardiovascular disease. (University of Texas MD Anderson Cancer Center)

Clinical Trials Comparison

A comparison of government- and pharma-funded clinical trials in oncology showed distinctly different trial designs and objectives. (SWOG Cancer Research Network)

Implications of Court Ruling

In a decision that could have far-reaching implications, a federal appeals court agreed with a lower court that alternative funding programs may not import Gilead drugs from overseas for resale in the U.S. (CNBC)

Examining Cancer Claims

Snopes examined the claims and facts surrounding President Trump aide Natalie Harp’s comments on how the “right-to-try” law helped her survive a rare bone cancer.

Disclaimer: This content is for informational purposes only and does not constitute medical advice. Always consult a healthcare professional for medical concerns.


Fuente: https://www.medpagetoday.com/hematologyoncology/othercancers/122712

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