Menopause Experts Release Guidance on Non-Hormone Therapy for Hot Flashes
CHICAGO — A multidisciplinary group of menopause experts developed new comorbidity-specific guidance on non-hormone therapy for moderate-to-severe vasomotor symptoms. First-Line Recommendations For patients whose primary menopausal symptoms are hot flashes and night sweats, first-line neurokinin (NK)-receptor antagonists are recommended. Alternative or second-line treatment options include selective serotonin reuptake inhibitors (SSRIs), serotonin-norepinephrine reuptake inhibitors (SNRIs), gabapentin, […]
Hospital’s Brain Tumor Cluster; Princess’s Lung Transplant; Plastic Surgery Deaths
Brain Tumor Report Brain tumors diagnosed in 11 nurses at Newton-Wellesley Hospital in suburban Boston were not caused by any exposures to chemicals, radiation, or anything else at their workplace, an independent report concluded. (NBC10 Boston) Ebola Outbreak Update Congo’s Ebola outbreak has yet to peak and may last for up to a year, Red […]
Triplet Could Become a New Standard in Tough-to-Treat CLL
Introducción Fixed-duration therapy with pirtobrutinib (Jaypirca) plus venetoclax (Venclexta) and rituximab improved progression-free survival (PFS) in patients with relapsed/refractory chronic lymphocytic leukemia (CLL), according to interim data from the phase III BRUIN CLL-322 trial. In the intent-to-treat population, median PFS was not estimable with the triplet therapy versus 39.7 months with venetoclax and rituximab, with […]
Prone Positioning Not a Big Help for Infant Bronchiolitis
Prone positioning of infants on high-flow nasal cannula oxygen support for bronchiolitis didn’t significantly reduce risk of progression to needing positive pressure ventilation, a large randomized trial showed. Escalation of care occurred in 15.0% of infants placed in the prone position and 20.8% in the supine position, a difference that did not reach statistical significance […]
FDA Staff Weigh In on Potential First mRNA Flu Shot
Ahead of an advisory committee meeting this week, FDA reviewers raised no serious efficacy or safety concerns about Moderna’s mRNA flu vaccine candidate for adults 50 and older, which has the potential to become the first such product approved by the agency. The trivalent influenza vaccine (mRNA-1010) is the one FDA controversially refused to consider […]
AI hospital summaries used safely, cut physician burnout
Clinical Takeaway: AI-drafted hospital summaries may ease documentation strain and burnout when doctors review them carefully. Missing details remain the main concern. Writing discharge summaries is one of the more time-consuming tasks in hospital medicine and a major driver of burnout. Earlier studies have evaluated the quality of AI-written summaries, but this study tested whether […]
Experts Question Impact of Trump’s Latest Effort on Fertility Care Coverage
Resumen de la propuesta The Labor Department’s proposed rule to make it easier for employers to offer a fertility benefit isn’t likely to result in many more employers doing so, although it may tip the scales for employers who were already considering it, experts said. “The proposal mostly changes the ease of offering, not the […]
Oncologist Cleared from Medical Isolation After Hantavirus Care
An oncologist traveling on the cruise ship at the center of a hantavirus outbreak has been cleared to leave a special biocontainment unit in Nebraska, where he was the lone American placed in isolation after he helped care for fellow passengers who became sick on board. Details of the Situation Stephen Kornfeld, MD, of Bend, […]
De-Escalated Treatment for Early Breast Cancer Continues to Gain Momentum
Resumen del Estudio The number of women skipping sentinel lymph node biopsy (SLNB) for early breast cancer doubled over a 5-year period to become the predominant strategy for low-risk disease, a prospective study showed. The proportion of patients who omitted SLNB increased from 25.5% in 2020 to 50.9% in 2025. Over the 5-year period, 69% […]
NYU Hospital Subpoenaed Over Gender-Affirming Care in Minors
A New York hospital system says it received a grand jury subpoena from federal prosecutors in Texas seeking information about children who received gender-affirming care and the medical providers who administered it. NYU Langone is the first hospital system to publicly acknowledge receiving a subpoena for such records as part of a federal criminal investigation. […]