Early Sugar Exposure and Cancer Risk; Melanoma Vaccine Win; ‘Antifreeze’ for CAR-T
Reduced Sugar Exposure and Cancer Risk People who had restricted sugar exposure during the first 2 years of life grew into adults with a lower risk of cancer. (American Journal of Clinical Nutrition) Antioxidants and Cervical Cancer Meanwhile, women who consumed a diet high in antioxidants had a lower risk of cervical cancer. (International Journal […]
Synovitis Confirmed as Prognostic in Hand Osteoarthritis, Regardless of Subtype
Patients with osteoarthritis (OA) of the hand face the same risk of structural progression when synovitis is present in the first carpometacarpal (CMC1) joint versus the interphalangeal joints, results of a prospective cohort study indicated. Among 201 hand OA patients followed for an average 3.4 years, those with high-grade synovitis in the CMC1 joint at […]
Novel Tuberculosis Vaccine Falls Short
An investigational tuberculosis (TB) vaccine didn’t top the standard bacillus Calmette-Guérin (BCG) vaccine at preventing infections in infants, a multicenter, phase III trial showed. Among nearly 6,900 newborns in sub-Saharan Africa, QuantiFERON-TB Gold Plus (QFT) conversion, indicating Mycobacterium tuberculosis infection or exposure, occurred in 5.3% of those who received the VPM1002 vaccine compared with 4.3% […]
Alfalfa Sprouts Linked to 15-State Food-Poisoning Outbreak
Introducción U.S. health officials say a food-poisoning outbreak tied to alfalfa sprouts and involving both Salmonella and E. coli has sickened people in 15 states. Casos reportados State officials announced the outbreak earlier this week, saying they documented more than three dozen cases in Minnesota and Wisconsin. On Friday, the CDC said the agency is […]
Senators Pan Trump Officials’ Demand for Health Data as Condition for Lifesaving Aid
Resumen de lo sucedido: Citing reporting by ProPublica, eight Democratic U.S. senators have criticized the Trump administration’s demands to access the health data of millions of people as a condition of giving lifesaving aid to other countries. In a letter to Secretary of State Marco Rubio, the senators, including minority leader Chuck Schumer of New […]
FDA-Approved Peanut Allergy Immunotherapy Exits Market
Not many allergists are mourning the exit of the first and only FDA-approved oral immunotherapy (OIT) product — peanut allergy treatment Palforzia — from the market. The standardized peanut protein product had been approved for treating peanut allergy in kids ages 4 to 17 years in 2020 but was discontinued in July. Manufacturer Stallergenes Greer […]
Will AI alone best physician-AI collaboration?
Clinical takeaway: When assessing an AI workflow for clinical practice, consider whether it will be used alone or with clinician review. Most clinicians have been handed a reassuring premise about AI: it can be a useful assistant to guide human decision-making. The American Medical Association favors the term “augmented intelligence,” and the American College of […]
4 Deaths Linked to Medical Device; New FDA Chief? Human-Chimp Hybrid Attempt
Note that some links may require registration or subscription. The FDA warned of a Class I recall of Becton Dickinson intraosseous vascular access system needle setsopens in a new tab or window because of a defect linked to 45 serious injuries and four deaths. The Ebola outbreak in Congoopens in a new tab or window […]
Knee Surgery Ends in Paralysis; Cassidy Flags FDA Nominee; Camilla on King’s Cancer
Knee Surgery Incident A routine knee replacement surgery ended in paralysis after a medication mix-up led to a patient reportedly getting “contaminated vials” that contained potassium. (USA Today) FDA Nominee Concerns Sen. Bill Cassidy, MD (R-La.), expressed “strong concerns” about Heidi Overton, MD, PhD, as the new nominee for FDA commissioner, given her support for […]
First autonomous blood draw robot authorized by FDA
Clinical takeaway: Expect supervised robotic draws in outpatient labs. Performance in trial use was comparable to trained phlebotomists on attempted sticks, but a human still handles anyone the device screens out. Blood draws are among the most common procedures in US medicine, and outpatient throughput often depends on how many trained phlebotomists are on the […]