ADA Reviewing Police Tussle; Obesity Trial Lawsuit; Retatrutide’s Early Access

The American Diabetes Associationopens in a new tab or window (ADA) asked for patience as its Audit and Governance Committee reviews the incident at this year’s annual meeting — when five prominent experts were removed by policeopens in a new tab or window — and prepares recommendations on the organization’s response.

Once-weekly somapacitan (Sogroya) was noninferior to daily growth hormone injections for boosting growth in treatment-naïve girls with Turner syndromeopens in a new tab or window while maintaining insulin-like growth factor 1 concentrations within a similar range, according to a phase III trial. (Journal of Clinical Endocrinology & Metabolism)

Novo Nordisk faces a shareholder lawsuitopens in a new tab or window alleging the company misled investors in statements regarding clinical trial results for its investigational weight-loss drug CagriSema. (CNBC)

Plastic surgeons are noticing more patients seeking treatmentopens in a new tab or window for “temporal hollowing” following use of GLP-1 agonists. (USA Today)

Eli Lilly announced it will allow more patients to apply for early access to its investigational obesity drug retatrutideopens in a new tab or window, weeks after granting a single 79-year-old patient special compassionate access. (Reuters via Yahoo!)

Rapid-acting insulin aspart-fsan (Garzulys) — the third biosimilar to Novolog — gained FDA approval for glycemic controlopens in a new tab or window in adults and pediatric patients with diabetes, said manufacturer Meitheal Pharmaceuticals.

Nearly 500,000 Medicaid beneficiaries with diabetes are projected to lose healthcare coverageopens in a new tab or window by 2034 without policy intervention, according to an ADA analysis.

The FDA issued new draft guidanceopens in a new tab or window for making generics of blockbuster diabetes and weight-loss drugs, including semaglutide (Ozempic, Wegovy) and tirzepatide (Mounjaro, Zepbound).

Following last year’s military ban on transgender service members, separation hearingsopens in a new tab or window for those challenging the order are taking place behind closed doors. (New York Times)

Randomized trials show that continuous glucose monitoring produces a modest reduction in HbA1c of about 0.3% on average in adults with type 2 diabetes, according to authors of a JAMA Internal Medicineopens in a new tab or window review.

Actor Ethan Suplee, known for his roles in “Remember the Titans” and “Boy Meets World,” offered words of caution regarding GLP-1 drugsopens in a new tab or window after losing 300 pounds. (Parade)

Women are sharing stories on social media saying that GLP-1 drugs helped them become pregnantopens in a new tab or window after struggling with infertility. (ABC News)

Novo Nordisk’s investigational IL-6 inhibitor ziltivekimabopens in a new tab or window failed to reduce risk of major adverse cardiovascular events in a phase III trial of patients with atherosclerotic cardiovascular disease, chronic kidney disease, and cardiovascular inflammation, the company announced.


Fuente: https://www.medpagetoday.com/endocrinology/generalendocrinology/122484

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