Compounded GLP-1s remain common, raising oversight concerns

Clinical takeaway: When patients use or request compounded GLP-1 medications, ask which pharmacy supplies the product and whether it meets appropriate sterile compounding standards. Compounded products may remain appropriate in select circumstances, but clinicians should discuss regulatory oversight and the limited evidence supporting added ingredients. Compounded semaglutide and tirzepatide became widely used during nationwide shortages […]
Stent Graft Recall; PMOS and Heart Disease; Disney World Cardiac Emergency

Stent Graft Recall Bolton Medical is recalling the Relay Pro Thoracic Stent Graft System due to difficulties in releasing the stent graft. As of April 23, the company has reported three deaths associated with this issue, according to an FDA alert. Heart Disease Research and Updates The American College of Cardiology added a Cardiovascular Shock […]
GLP-1 Maker Sued Over Ads; Vaginal Estrogen; Melinda Gates Talks Perimenopause

GLP-1 Lawsuit Novo Nordisk sued rival drugmaker Eli Lilly, alleging false advertising claims about relative weight-loss drug performance. (Reuters via NBC News) Surge in GLP-1 Use GLP-1 drug use surged from 2017 to 2022, jumping 230% in adults with diabetes and 643% in those without, national data indicated. (Journal of the American Heart Association) Popular […]
Drugs for Dry AMD Linked to Thickening of Retinal Nerve

MONTREAL — Complement inhibitors to treat geographic atrophy (GA) were associated with thickening of the retinal nerve fiber layer (RNFL), which could be helpful or pathologic, according to a study reported here. Both FDA-approved complement inhibitors were linked to an increase in the RNFL, whereas untreated GA, or dry age-related macular degeneration (AMD), and anti-VEGF […]
Judge Questions Hegseth’s Testosterone Policy Amid Military’s Transgender Care Ban

Introducción Defense Secretary Pete Hegseth’s new initiative to test and treat troops for low testosterone has prompted a federal judge to question the differences between that kind of testosterone replacement therapy (TRT) and hormone treatment for transgender men in the military. Contexto Legal U.S. District Judge Ana Reyes in Washington raised the question Wednesday in […]
Captain Kirk Survives Cancer; Nonsmokers’ Lung Cancer Crisis; Catfish and Cancer

William Shatner’s Cancer Journey Actor William Shatner, known as Captain Kirk from the original “Star Trek” television series, along with his daughter, openly discusses his battle with advanced cancer. This highlights the critical importance of early detection and ongoing research in cancer treatment. (ABC News) Texas Cancer Research Funding Challenges Despite substantial investments in cancer […]
Inside the Intestinal Crypt: Untold Stories of Cyclospora

Imagine the scene: It’s May 1991, and a New York gastroenterologist will soon fly home from a medical meeting in Atlanta, all the while pondering a perplexing illness in Nepal. As Bradley Connor, MD,opens in a new tab or window had just learned, many expats in Kathmandu had been suffering severe diarrhea. But here was […]
You’ve Heard of Cyclospora. What Other Parasites Can You Catch From Food?

As health officials track cyclosporiasis casesopens in a new tab or window in multiple states, experts note that there are plenty of other parasites that people can contract from food. Types of Parasites These fall into two main categoriesopens in a new tab or window: protozoa — like Cyclospora, the one causing “explosive diarrheaopens in […]
FDA Approves Tylenol With Naproxen Combination

The FDA approved a combination tablet of 325-mg acetaminophen and 110-mg naproxen sodium (Tylenol with Naproxen) for over-the-counter (OTC) pain relief, the agency announcedopens in a new tab or window Friday. The opioid-free combination tablet is indicated for the temporary relief of minor aches and pains from headaches, backaches, muscular aches, toothaches, menstrual cramps, and […]
NIH Funding Flows Slowly to Cancer Centers

Last year, National Cancer Institute (NCI)-designated cancer centers were worried about losing their statusopens in a new tab or window due to numerous delays in the grantmaking process. More than a year later, leadership at these centers said the situation is more stable — but the funding is coming through much more slowly. The Dartmouth […]